[PubMed] 35.Perishable A, Advisory
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Epithalon (Epitalon) Primary uses: Longevity Telomere lengthening Sleep regulation (melatonin) Anti-aging Typical dosing: 10mg per cycle 1mg daily for 10 days Cycles: Every 3-6 months Administration: Subcutaneous injection Special notes: Strong evidence for telomere lengthening Used in anti-aging protocols Well-tolerated Improves sleep regulation (pineal gland function) Thymosin Alpha-1 Primary uses: Immune system optimization Anti-viral effects Longevity Chronic illness support Typical dosing: 0.5-1mg, 2-3 times per week Duration: Ongoing or cycles Administration: Subcutaneous injection Special notes: Powerful immune modulator FDA-approved for hepatitis (Zadaxin) Well-studied safety profile Used in longevity protocols Selank Primary uses: Anxiety reduction Cognitive enhancement Immune modulation Neuroprotection Typical dosing: 250-500mcg daily Injectable or intranasal Duration: 2-4 weeks, then break Administration: Subcutaneous injection or intranasal spray Special notes: Developed in Russia Anxiolytic without sedation Improves focus and mental clarity No dependence or withdrawal Semax Primary uses: Cognitive enhancement Focus and concentration Neuroprotection Stroke recovery Typical dosing: 300-600mcg daily Injectable or intranasal Duration: 2-4 weeks, then break Administration: Subcutaneous injection or intranasal spray Special notes: Powerful nootropic Increases BDNF (brain-derived neurotrophic factor) Improves learning and memory Developed in Russia Sexual health peptides These enhance libido, arousal, and sexual function

This has recently been used to shuttle the entire and fully functional enzymes to the brain and into subcellular compartments using the transferrin receptor: the enzyme -glucocerebrosidase coupled to TfR-binding moieties and the amyloid-beta antibody gantenerumab fused also with the TfR-binding moieties have been successfully transferred to the brains of mice and non-human primates [319, 320]